Every time Clive Wearing sees his wife, he greets her as if it's been ages. Deborah hasn't gone anywhere, but since 1985, Clive has lived every moment believing that he just woke up from a coma.
Before his illness, Clive was an accomplished musician. Then, he contracted herpesviral encephalitis, a virus that infects the central nervous system. Clive recovered, but the part of his brain that stores memories had been completely destroyed.
The only person Clive remembers is his wife, Deborah. He doesn't believe that he's ever seen a doctor for his condition, and doesn't remember his own children. Every 30 seconds or so, Clive "wakes up for the first time," only to immediately repeat the cycle.